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Blizard Institute - Faculty of Medicine and Dentistry

About

Advancing blood transfusion research

Our research focuses on developing and delivering research projects that directly address transfusion management of a broad group of patients (e.g. bleeding, haemoglobinopathy, patient blood management etc.). Our research themes include:

  • Translational research
  • Data Science
  • Education and staff development
  • Healthcare Economics

Translational research

 

We develop and conduct clinical studies relating to blood components that underpin the evidence for safe and appropriate use of blood across different aspects of patient blood management and evaluate alternative products to transfusion. We work closely with component development laboratory at NHSBT to develop novel blood components and take them into the early clinical phase trials. We have studied the epidemiology of major bleeding due to acquired causes (e.g. obstetrics, surgery etc.) resulting in development and delivery of several clinical trials including SWiFT and PROPEHSY-2 trial.

Data science

 

Using routinely collected data and data science techniques our group is exploring the outcomes of patients to evaluate current and novel blood components and products to improve patient’s care.

Education

 

We provide a highly conducive environment for the delivery of postgraduate training programmes and support scientists and clinicians development across three organisations.

Healthcare economics

TAG collaborates closely with the Health Economics team at the Health Economics Policy Research Unit of the Wolfson Institute of Population Health (HEPRU-WIPH) to enhance transfusion care through robust economic analysis.

We focus on evaluating the value for money of new transfusion interventions by analysing their costs, patient outcomes, and impact on healthcare systems. We apply a range of methods, including cost-effectiveness, cost-utility, and budget impact analysis, to support evidence-based decision-making.

Drawing on real-world data, we assess hospital activity, blood use, and outcomes to understand how interventions affect everyday practice. We also evaluate digital blood-management platforms—such as electronic ordering and bedside scanning—for their role in improving efficiency and safety.

Our team contributes economic expertise to clinical trials like PROPHEsy II and BETC, and conducts systematic reviews to inform national guidelines and transfusion policy.

By quantifying resource use, outcomes, and system-wide effects, we help hospitals, blood services, and policymakers make high-value, evidence-informed decisions in transfusion care.

 

Meet the team

Current students

Dr Chibuzo Mowette
PhD student

Dr Harriet Tucker
PhD student

Ms Florence Oyekan
PhD student

Deborah Awogbade
MSc student

Former students

Dr Andrea Rossetto
PhD - 2024

Dr Suzanne Forbes, MD
PhD - 2024

Dr Ruchika Kohli, MD
PhD - 2021

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